This publication is a result of Blue Solutions’ second Regional Forum on Solutions for Oceans, Coasts and Human Well-being in Latin America and the Wider Caribbean Region. This four-day workshop was held in Cancún, Mexico in April 2015. During this event more than 40 participants presented their positive examples and engaged with the larger audience in discussions around how these examples can be adapted to address pressing challenges faced in other regions or sectors in Latin America and the Wider Caribbean. This publication compiles 50 blue solutions from Latin America and the Wider Caribbean region, most of which were presented. The cases are summarized within this publication and focus on topics such as marine protected areas, sustainable tourism, sustainable fisheries, sustainable livelihoods, conservation of resources and biodiversity and mitigation of the effects of climate change. It is an inspiring guide through activities and projects towards the protection and integrated, sustainable management of valuable and vulnerable coastal and marine ecosystems.